The executive told the gathering's meeting the UK must change after the "calm insurgency" of the Brexit vote, encouraging individuals to "grab the day".
Work were currently seen as the "terrible party" and just the Tories would "go to bat for the feeble... up to the capable".
Government ought to be a "power for good" to help working individuals, she contended.
In her set-piece discourse in Birmingham, under three months after she got to be leader, Mrs May said her vision was of a nation "where everybody plays by the same standards and where each and every individual, paying little mind to their experience or that of their folks, is allowed to be all they need to be".
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The vote to leave the EU, she said, was an "once-in-an era opportunity to change the nation for good" and compose another page in its history.
Promising to manufacture a "more grounded, more pleasant and brighter future", she asked individuals whichever way they had voted in the submission "to accompany me as we ascend to meet this minute, accompany me and together how about we grab the day".
The vote to leave the EU, she said, showed a yearning for more noteworthy control as well as mirrored the profound divisions that had developed in the nation over eras, with working individuals time and again overlooked by the "favored and effective".
"It was not the well off who made the greatest penances after the money related emergency, it was normal common laborers families," she said.
"In case you're one of those individuals who lost their employment, who stayed in work yet on lessened hours, took a compensation cut as family unit bills soared, or - and I know many people don't care to concede this - somebody who ends up out of work or on lower compensation due to low-talented migration, life basically doesn't appear to be reasonable.
"It feels like your fantasies have been relinquished in the administration of others."
Promising to assemble a "joined England established in an inside ground", she said her legislature would secure employments and "repair" free markets when they didn't work legitimately.
Setting out a "mindful private enterprise" plan, she said the legislature would "follow" organizations that viewed paying duty as "a discretionary additional", test those which selected "shoddy remote work" to the detriment of English specialists and, in a reference to the breakdown of retailer BHS, denounce the individuals who "take out gigantic profits while realizing that the organization benefits is going to become penniless".
Past Tory pioneers have tried to decrease state mediation, yet Mrs May said her legislature would make a move to recognize bad form, discover arrangements and drive change.
In a discourse in which there were no new strategy declarations Mrs May spoke broadly about the qualities which would shape her prevalence with the PM, saying Work did not have "a syndication on sympathy", censuring the gathering's "unctuous affectation of good predominance".
"We should clarify that they have surrendered the privilege to call themselves the gathering of the NHS, the gathering of the laborers, the gathering of open workers."
Furthermore, to immense commendation from the corridor, she flipped the "awful party" tag - which was the manner by which she broadly said some saw the Traditionalists in 2002 - on to the Work Party taking after their late rancorous authority challenge.
She restated her backing for amplifying particular instruction in the state segment and growing punctuation schools, saying they had a part to play "where guardians need them and where they will enhance instructive guidelines".
'Force of government'
Making a pitch for the Tories to be the gathering of "customary regular workers individuals", she said: "Simply listen to the way a considerable measure of legislators and pundits discuss the general population.
"They discover their patriotism tacky, their worries about migration parochial, their perspectives about wrongdoing illiberal, their connection to their professional stability badly arranged.
"They discover the way that more than 17m individuals voted to leave the European Union essentially confounding."
Rejecting the marks of the "communist left and the libertarian right", she told Tory supporters: "It's an ideal opportunity to recall the great that legislature can do.
"Where numerous consider government to be an issue, I need to show it can be a piece of the arrangement."
"While government does not have every one of the answers, government can and ought to be a power for good; that the state exists to give what unique individuals, groups and markets can't; and that we ought to utilize the force of government for the benefit of the general population."
BBC political manager Laura Kuenssberg said in underwriting a dissident state, Mrs May was making a "striking offer for irritated Work supporters".
Yet, she said the head administrator would eventually be judged on her activities - in zones like training and wellbeing - regarding whether individuals would "become tied up with her vision".
'Terrible vision'
Work said the discourse denoted an unequivocal movement to one side, with a "retrogressive" schools approach and no activity to handle a NHS in "monetary emergency".
The Lib Dems said their previous coalition accomplices were presently "divisive, rash and merciless" while the SNP assaulted "repellent" proposition - reported on Tuesday - which could compel organizations to explain what extent of their workforce is remote.
"Theresa May's vision of Brexit England is a profoundly revolting one - a nation where individuals are judged not by their capacity or their commitment to the benefit of all yet by their origination or by their travel permit," said SNP pioneer Nicola Sturgeon.
The end discourse in Birmingham was Mrs May's second gathering address this year, after she talked about Brexit on the very first moment.
The UK's way out from the EU has posed a potential threat over the four-day meeting, which started with Mrs May affirming the planning of the UK's formal Brexit trigger, which will happen before Walk 2017.
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